scholarly journals Osmotic resistance of erythrocytes from patients with carcinoma

Cancer ◽  
1949 ◽  
Vol 2 (3) ◽  
pp. 503-509
Author(s):  
T. Hastings Wilson ◽  
Walter E. Landmesser
Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1050
Author(s):  
Sylwia Cyboran-Mikołajczyk ◽  
Robert Pasławski ◽  
Urszula Pasławska ◽  
Kacper Nowak ◽  
Michał Płóciennik ◽  
...  

Long-term high fat-carbohydrates diet (HF-CD) contributes to the formation of irreversible changes in the organism that lead to the emergence of civilization diseases. In this study, the impact of three-month high-fat diet on the physical properties of erythrocytes (RBCs) was studied. Furthermore, the biological activity of Cistus incanus L. extracts, plant known with high pro-health potential, in relation to normal and HF-CD RBCs, was determined. Obtained results have shown that, applied HF-CD modified shape, membrane potential and osmotic resistance of erythrocytes causing changes in membrane lipid composition and the distribution of lipids. The impact of HF-CD on physical properties of RBCs along with atherosclerotic lesions of the artery was visible, despite the lack of statistically significant changes in blood morphology and plasma lipid profile. This suggests that erythrocytes may be good markers of obesity-related diseases. The studies of biological activity of Cistus incanus L. extracts have demonstrated that they may ameliorate the effect of HF-CD on erythrocytes through the membrane-modifying and antioxidant activity.


1927 ◽  
Vol 25 (2) ◽  
pp. 92-93 ◽  
Author(s):  
C. D. Leake ◽  
C. Backus ◽  
H. Burch ◽  
K. O'Shea

2013 ◽  
Vol 155 (2) ◽  
pp. 175-178 ◽  
Author(s):  
E. E. Khirazova ◽  
M. G. Golubeva ◽  
M. V. Maslova ◽  
A. V. Graf ◽  
A. S. Maklakova ◽  
...  

Author(s):  
N. E. Kobzar ◽  
V. P. Mikhailov ◽  
V. V. Porseva

Introduction. Methyl-β-cyclodextrin is a potent acceptor of cellular membrane cholesterol and, at the same time, used as a solubilizer, which makes it a potential target for targeted delivery of hydrophobic compounds.Aim. To assess the effect of administration of methyl-β-cyclodextrin containing cholesterol on the degree of lung hydration and osmotic resistance of erythrocytes against the background of pulmonary edema in adult rats caused by the administration of mezaton.Materials and methods. We investigated the degree of hydration of the lungs by the value of the pulmonary coefficient and their dry residue. Osmotic resistance of erythrocytes were assessed by the intensity of their hemolysis in a series of hypotonic sodium chloride solutions in adult male Wistar rats (220±40 g) of the control group (intact, n=10) and two experimental groups with pulmonary edema caused by the administration of mezaton (n=10) and with the subsequent introduction of a water-soluble complex cholesterol-methyl-β-cyclodextrin against the background of the development of pulmonary edema (n=10). We used additional criteria for assessing the osmotic resistance of erythrocytes: minimum resistance – the concentration of sodium chloride solution, at which the first “weak” erythrocytes begin to hemolyze; maximum resistance is the concentration of sodium chloride solution at which all or almost all erythrocytes hemolyzed.Results. The introduction of mezaton led to the development of pronounced hemolysis and hydration of the lungs with the development of their edema and a narrowing of the range of minimum and maximum osmotic resistance of erythrocytes. The introduction of a complex of cholesterol with methyl-β-cyclodextrin after edemogenic exposure led to a decrease in the severity of pulmonary edema, determined by a decrease in the pulmonary coefficient and an increase in the dry residue, and to an increase in the osmotic resistance of erythrocytes with an expansion of the range of their minimum and maximum osmotic resistance.Conclusion. The introduction of a water-soluble complex of cholesterol with methyl-β-cyclodextrin against the background of the development of hemodynamic pulmonary edema significantly reduced the degree of hydration of the lungs, which combined with an increase in the osmotic resistance of erythrocytes.


2019 ◽  
Vol 29 (2) ◽  
pp. 168-168
Author(s):  
Olena Chabanenko ◽  
◽  
Gennadiy Kovalov ◽  
Inessa Iefimova ◽  
◽  
...  

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